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Risk factors Factors that increase your risk of developing Stevens-Johnson syndrome include: Among people with HIV, the incidence of Stevens-Johnson syndrome is about times greater than among the Steven jhonson syndrome population.
A weakened immune system. If you have a weakened immune system, you may have an increased risk of Stevens-Johnson syndrome. A history of Stevens-Johnson syndrome. If you've had a medication-related form of this condition, you are at risk of a recurrence if you use that drug again.
A family history of Stevens-Johnson syndrome.
If an immediate family member has had Stevens-Johnson syndrome or a related condition called toxic epidermal necrolysis, you may be more susceptible to developing Stevens-Johnson syndrome too. If you have a gene called HLA-Byou have an increased risk of Stevens-Johnson syndrome, particularly if you take certain drugs for seizures, gout or mental illness.
Families of Chinese, Southeast Asian or Indian descent are more likely to carry this gene. Complications Stevens-Johnson syndrome complications include: Secondary skin infection cellulitis.
Cellulitis can lead to life-threatening complications, including sepsis. Sepsis occurs when bacteria from an infection enter your bloodstream and spread throughout your body. Sepsis is a rapidly progressing, life-threatening condition that can cause shock and organ failure. The rash caused by Stevens-Johnson syndrome can lead to inflammation in your eyes.
In mild cases, this may cause irritation and dry eyes.
In severe cases, it can lead to extensive tissue damage and scarring that results in visual impairment and, rarely, blindness. The condition may lead to acute respiratory failure.
When your skin grows back following Stevens-Johnson syndrome, it may have abnormal bumps and coloring. And you may have scars. Lasting skin problems may cause your hair to fall out, and your fingernails and toenails may not grow normally.
Prevention Consider genetic testing before taking certain drugs. If you are of Chinese, Southeast Asian or Indian descent, talk with your doctor before taking carbamazepine Carbatrol, Tegretol.
This drug is useful to treat epilepsy, bipolar disorder and other conditions. If you've had this condition, avoid the medication that triggered it. If you've had Stevens-Johnson syndrome and your doctor told you it was caused by a medication, avoid that drug and others like it.
This is key to preventing a recurrence, which is usually more severe than the first episode and can be fatal. Your family members also might want to avoid this drug because some forms of this condition have a genetic risk factor.Stevens-Johnson syndrome (SJS) is a rare and serious condition of your skin and mucus membranes.
SJS will cause you to lose up to 10% of your outer layer of skin. SJS is usually caused by a response to a medicine you have been taking. 43 rows · Oct 08, · Stevens-Johnson syndrome /toxic epidermal necrolysis (SJS/TEN) is a very .
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe mucocutaneous reactions, most commonly triggered by medications, characterized by extensive necrosis and detachment of the epidermis.
Mucous membranes are affected in over 90 percent of patients, usually at two or more distinct sites (ocular, oral, and genital). Stevens–Johnson syndrome (SJS) is a type of severe skin reaction. Together with toxic epidermal necrolysis (TEN) and Stevens-Johnson/toxic epidermal necrolysis (SJS/TEN), it forms a spectrum of disease, with SJS being less severe.
Aug 17, · August 18, Chief Complaint. Total body rash with mucosal involvement.
History of Present Illness. A year-old female was prescribed trimethoprim-sulfamethoxazole by her primary care provider for a lower extremity infection.
Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a severe skin reaction most often triggered by particular medications. Although Stevens-Johnson syndrome and toxic epidermal necrolysis were once thought to be separate conditions, they are now considered part of a continuum.